Nitric Acid Oxidation of Benzyl Nitrates

Nitric oxide, nitrates and ischaemic preconditioning.

1. Introduction model produced significant protection against myocardial cell death. There appears to be a bimodal distribution of In 1986 Furchgott first suggested that endothelial-de-protection with an initial more powerful but short-lived rived relaxing factor might be nitric oxide (NO) [1]. Since phase existing between 1 and 3 h ('Early Preconditioning') then the remarkable role of nitric o...

Atomistic oxidation mechanism of a carbon nanotube in nitric acid.

Motivated by recent experiments, we investigate how NO3-SWNT interactions become energetically favorable with varying oxidation state of a single-walled carbon nanotube (SWNT) using first-principles calculations. Chemisorption becomes less endothermic with respect to physisorption when the SWNT oxidation state is elevated. Importantly, the dissociative incorporation of an oxygen atom into the S...

Modifications in the nitric acid oxidation of D-glucose.

The nitric acid oxidation of D-glucose was reinvestigated in an effort to better understand and improve the oxidation and subsequent work up steps. The oxidation was carried out using a computer controlled reactor employing a closed reaction flask under an atmosphere of oxygen which allowed for a catalytic oxidation process with oxygen as the terminal oxidant. Removal of nitric acid from produc...

Inorganic and Organic Nitrates as Sources of Nitric Oxide

Nitrate esters as nitric oxide donors: SS-nitrates.

[structure: see text]. The important biological secondary messenger NO can be generated from exogenous nitrovasodilators and NO donors. Nitrate esters are nitrovasodilators and NO mimetics, believed to be biotransformed to NO in vivo. On the basis of a mechanistic hypothesis, nitrates have been synthesized that release NO at significant rates in neutral aqueous solution in the presence only of ...